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KMID : 1101120210180030162
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Journal of Sleep Medicine
2021 Volume.18 No. 3 p.162 ~ p.166
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Efficacy of Oxcarbazepine for Sleep-Related Leg Cramps: A Retrospective Study
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Ahn Seon-Jae
Shin Yong-Won
Jung Ki-Young
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Abstract
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Objectives: Sleep-related leg cramps (SRLC) are common among older people. Severe clinical symptoms of SRLC usually cause great discomfort to patients. To date, many treatment drugs have been tried; however, there are currently no drugs approved for treating this condition. We aimed to assess the efficacy of a new drug, oxcarbazepine (OXC), in the treatment of SRLC.
Methods: We retrospectively analyzed clinical outcomes following OXC administration. A daily dose of 150 mg OXC was prescribed to control nocturnal leg cramps. Clinical outcomes were measured using the Clinical Global Impression Scale to confirm the effectiveness of OXC.
Results: A total of 88.9% (16/18) of patients clinically improved four weeks after OXC prescription, and 94% (15/16) of patients continued to improve at the last follow-up (3?6 months). None of the patients complained of side effects related to 150 mg OXC.
Conclusions: OXC may be a new medical option for treatment of SRLC.
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KEYWORD
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Sleep, Muscle cramp, Oxcarbazepine
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